The goal of this project is to revolutionize current eye care diagnostics and disease management by creating IMAGE-R, a computer-aided detection (CAD) system for retinal diseases, which makes use of state-of-the-art machine learning techniques. IMAGE-R provides eye care professionals with a comprehensive solution for fast, accurate, and cost-saving retinal disease detection (for screening) as well as quantification (for disease management). The system will be applicable for the most frequent retinal diseases (age-related macular degeneration (AMD), diabetic retinopathy (DR) and glaucoma), be compatible with color fundus (CF) retinal images and optical coherence tomography (OCT) imaging data, and be widely accessible to eye care providers through a cloud-based platform. This project is a collaboration between qurAI Eye Lab, Retinai Medical Ag, Thirona B.V., and University Of Bern – Artorg Center For Biomedical Engineering Research. The project is funded within the Eurostars programme.